Caffeine-fuelled fix for runaway eye treatment
Crystal designed to have stronger hydrogen bonds
Sulfacetamide (SACT) is often lost on blinking and in tears when applied as a treatment for conjunctivitis and other ocular ailments. This leads to the inconvenience and complications of applying larger and more frequent doses of SACT.
Various schemes have been investigated, including trapping SACT in bioadhesive microspheres, to slow drug release and prevent its washout. But these either limited the drug’s bioavailability or weren’t suitable to market.
To solve the problem, Ashwini Nangia and colleagues at the University of Hyderabad in India, looked to cocrystals.
This article provides a link to coverage by Chemistry World
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