HPLC-free synthesis slashes protein production time
Tagging system may make building biologically relevant proteins faster, cheaper and greener
Chemists in Germany have devised a faster, cheaper and greener way to synthesise proteins which avoids the need to use high pressure liquid chromatography (HPLC).
Oliver Seitz and his team at Humboldt University of Berlin, Germany, have come up with a way to do in three days what used to take a month, by eliminating the need for HPLC. ‘In principle this should also be relatively easy to automate,’ says Seitz. ‘It involves only liquid dispensing and filtration. Any high throughput facility already has robotic dispensers that can do this anyway, and they could be reformatted for our protein synthesis method.’
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