Distillates - January 2012
A look at recent chemical science research from Chemistry World
Functionalised fibre catches flu before you do
Scientists in China have developed a fibre that can trap the flu virus, which could be used in face masks and air filters to help to control the spread of the disease.
Every year, millions of people find themselves suffering the aches and pains of flu, and in the very worst cases - around 300,000 per year - the infection is fatal. Recent flu pandemics have illustrated the severity and potency of the influenza virus and the continuing threat of future outbreaks demands rapid and effective controls.
When the flu virus infects a host the viral protein hemagglutinin attaches itself to carbohydrate chains on the host's cells. 'This protein-carbohydrate interaction provides an interesting target for antiviral developments,' says team leader Xuebing Li at the Chinese Academy of Sciences, Beijing. His team exploited this well known interaction by attaching the same carbohydrate chains to the natural polysaccharide chitosan, creating a fibre that can trap the flu virus. 'Multivalent presentation of the carbohydrate on a scaffold enhances the virus binding,' says Li, adding 'chitosan's unique biological properties and perfect fabricability make it an ideal scaffold'.
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