Fundamental topics such as stereochemistry are taught in 2 or 2.5D - the Cambridge Structural Database provides an interactive 3D solution
Chemistry is a 3D subject. Topics such as stereochemistry, chirality, conformation, metal coordination geometry and molecular symmetry are fundamental building blocks of the subject. However, despite the ready availability of interactive molecular graphics software, often at zero cost, structural principles are still frequently taught using 2D images, embellished when required with wedge and dot bonds to provide a 2.5D representation at best. Students must then use their own mental agility to visualise, rotate, invert and perceive symmetry in these chemical objects. In itself, this is fine - every subject needs its shorthand notations - but there is a steep learning curve to reach a point where visual acuity can transform 2D and 2.5D images into full 3D imagery. While 3D graphics and animations using modelled and limited experimental data are extremely valuable, a significant source of 3D structures of varied complexity and broad chemical coverage is needed.
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