Chemistry Outreach: Aspirin

No comments

Students undertake the synthesis and analysis of aspirin.

Downloads

Aspirin experiment
PDF, Size 7.21 mb

No comments

Level

16-18 years

Use

Specification

Northern Ireland
- A/AS level
  - CCEA Chemistry
    - Unit A2 2: Analytical, Transition Metals, Electrochemistry and Organic Nirtrogen Chemistry
      - 5.11 Chemistry in medicine
        5.11.7 recall the synthesis of aspirin from salicylic acid using ethanoic anhydride and reasons for its use as a sodium salt;
        5.11.8 use TLC and GLC MS to identify drugs and their purity (link with Section 5.4);
England
- A/AS level
Scotland
- Higher
  - SQA Chemistry
    - 2. Nature's chemistry
      - (d) Esters, fats and oils
        An ester is a molecule containing an ester link: ─COO─.
- Advanced Higher
  - SQA Chemistry
    - Researching Chemistry
      - Practical skills and techniques
        Melting point
        Candidates should be familiar with determination of melting point and mixed melting point experimental procedures.
        Thin-layer chromatography
        Candidates should be familiar with thin-layer chromatography experimental procedure.
        Recrystallisation
        Candidates should be familiar with recrystallisation experimental procedure.
      - Experiments
        7A. Preparation of aspirin (acetyl salicylic acid).
    - Developing skills for learning, life and work
      - Working with others
        Learning activities provide many opportunities, in all areas of the Course, for learners to work with others. Practical activities and investigations, in particular, offer opportunities for group work, which is an important aspect of chemistry and should…
Wales
- A/AS level
  - WJEC Chemistry
    - Unit 4: ORGANIC CHEMISTRY AND ANALYSIS
      - 4.8 Organic synthesis and analysis
        (b) principles underlying the techniques of manipulation, separation and purification used in organic chemistry
        (g) use of chromatographic data from TLC/paper chromatography, GC and HPLC to find the composition of mixtures
        PRACTICAL: Paper chromatography separation, including two-way separation

Resource
Aspirin screen experiment

Get students aged 16–18 running their own organic synthesis on a computer or tablet before taking part in the real thing. This resource also features an in-depth practical guide and a set of worksheets covering the theory.
Resource
Limestone weathering

This activity is designed for students aged 11-14. It can be used to reinforce work on the reactions of carbonates with acids as well as the chemical weathering of rock.
News
Linking energy, structure and reactivity

2023-08-15T09:20:00Z By David Read

Discover how students reason about energy and chemical structure – and how to boost their understanding