Microscale chemistry

Some reactions of sulfur dioxide

Observe the reactions of sulfur dioxide with potassium manganate (IV), iodide/iodate mixture and indicator solution. Includes kit list and safety instructions. 

The determination of copper in brass

Try this microscale class practical to investigate how much copper there is in brass using nitric acid. Includes kit list and safety instructions.

Microscale reactions of hydrogen sulfide

Observe the reactions of hydrogen sulfide with lead nitrate, silver nitrate and potassium manganate(VII) in this microscale practical. Includes kit list and safety instructions.

Microscale reactions of ammonia

Try this practical to explore the reactions of ammonia with indicator solution, copper(II) sulfate solution and Nessler’s reagent. Includes kit list and safety instructions.

Measuring density

By measuring the relative mass of seawater and tap water, students will be able to discover the density of these liquids. Includes kit list and safety instructions. 

The chemistry of thiosulfate ions

Sodium thiosulfate has several interesting reactions with a variety of chemicals. This experiment will let students explore and record these reactions. Includes kit list and safety instructions.

Some reactions of nitrogen dioxide

Using a range of chemicals and solutions, students can create an experiment that will explore some of the reactions of nitrogen dioxide. Includes kit list and safety instructions.

Testing acids and bases on a microscale

Test various substances with indicator solution and look for colour changes in this microscale class practical. Includes kit list and safety instructions.

Mass changes in chemical reactions

Perform two chemical reactions to see whether any mass changes occur in this microscale class practical. Includes kit list and safety instructions.

The oxidation of cyclohexanol by nitric acid

Perform a ring opening oxidation using nitric acid to produce the dicarboxylic acid, 1,6-hexanedioic acid (adipic acid) – and then use the solid crystals that form to determine a melting point. Includes kit list and safety instructions.

Exploring the chemistry of chromium, molybdenum and tungsten

Discover how transition elements differ in aspects of colour, precipitate formation, changes in oxidation state and equilibria. Includes kit list and safety instructions.

Brady’s test for aldehydes and ketones

Identify aldehydes and ketones using Brady’s reagent (2,4-dinitrophenylhydrazine) in this microscale experiment. Includes kit list and safety instructions.

The chemical properties of phenol

Observe and interpret some of the chemical reactions of hydroxybenzene (phenol), by adding five different substances to a Petri dish, and noting down findings. Includes kit list and safety instructions.

Preparing ethyne on a microscale

Generate ethyne gas with calcium carbide and test its properties in this microscale class practical. Includes kit list and safety instructions.

Observing chemical changes

Try this microscale practical to explore the chemical changes in displacement, redox and precipitation reactions. Includes kit list and safety instructions.

Diffusion of gases on a microscale

Try this class practical to explore the diffusion of gases and how relative molecular mass affects rate of diffusion. Includes kit list and safety instructions.

Redox chemistry with dichromate ions

Observe the colour changes that occur with the reduction of dichromate ions by hydrogen peroxide. Includes kit list and safety instructions.

Oxidation states of iron

Compare the two main oxidation states of iron and consider explanations for differences in this microscale practical. Includes kit list and safety instructions.

Microscale reactions of metals with acids

Try this class practical to explore reactivity series with various metals as they react with acids on a microscale. Includes kit list and safety instructions.

Unsaturation test with potassium manganate(VII)

Use a solution of potassium manganate to test for unsaturation in organic compounds in this microscale practical. Includes kit list and safety instructions.

Properties of group 2 elements

Microscale experiment where various anion solutions are added to drops of group 2 element cations. Includes kit list and safety instructions.

Testing for unsaturation with bromine on a microscale

Try this class experiment to prepare elemental bromine and use it to test for unsaturation in organic compounds. Includes kit list and safety instructions.

Oxygen and methylene blue

Reacting hydrogen peroxide, and potassium manganate together will produce detectable oxygen so by using methylene blue solution, and a gas generating apparatus students can test for the presence of oxygen in this practical. Includes kit list and safety instruction.

Synthesis of aspirin on a microscale

Use this class practical to produce aspirin in a microscale esterification reaction using phosphoric acid as a catalyst. Includes kit list and safety instructions.

Energy changes in neutralisation

Study energy changes in two chemical reactions using thermometer strips to measure temperature in this experiment. Includes kit list and safety instructions.

Formation of TCP (2,4,6-trichlorohydroxybenzene)

Delve into preparing TCP by reacting hydroxybenzene (phenol) with chlorine gas, and create this distinctive smelling compound.

Investigating redox reactions on a microscale

Carry out two redox reactions and observe and interpret the results in this microscale class practical. Includes kit list and safety instructions.

The microscale synthesis of indigo dye

Carry out a microscale organic synthesis, the result of which will leave students with indigo dye. Includes kit list and safety instructions.

Finding out how much salt there is in seawater

Use the microscale titration apparatus to titrate silver nitrate solution against sea water

The treatment of oil spills

Tackle the real-life environment problem of oil spills in your classroom, by creating and then treating a micro version of an oil event. Includes kit list and safety instructions.

Some reactions of carbon dioxide

Create carbon dioxide from marble chips and acid, then test for its reaction with barium hydroxide by observing the carbonate precipitate. Includes kit list and safety instructions.

The microscale synthesis of azo dyes

Synthesise an azo dye, and use it to change the colour of cotton, with this class experiment. Includes kit list and safety instructions.

Sulfate and carbonate solubility of Groups 1 and 2

Try this microscale practical to explore the properties of elements in Groups 1 and 2 as they form various precipitates. Includes kit list and safety instructions.

Measuring an equilibrium constant on a microscale

Use your microscale titration apparatus to determine the equilibrium constant for the reaction between silver(I) and iron(II) ions

Exploring the properties of the carvones

Test the smell of each enantiomer of carvone and detect the differences

Measuring the amount of vitamin C in fruit drinks

Explore ascorbic acid in fruit drinks through titration in this experiment, with specimen results and calculations, stock solutions, and detailed notes included. 

Displacement reactions of metals on a microscale

Examine the reactions between various metals and metal salt solutions in this microscale class practical. Includes kit list and safety instructions.

Electrolysis using a microscale Hoffman apparatus

Investigate the electrolysis of sodium sulfate solution using a microscale Hoffman apparatus in this class practical. Includes kit list and safety instructions.

The chemistry of silver

Discover the properties of silver compounds with redox reactions, complex formation and colour/state changes. Includes kit list and safety instructions.

Transition elements and complex compounds microscale experiment | 16–18 years

Try this microscale practical investigating the transition elements, complex formation and change in oxidation state. Includes kit list and safety instructions

Analysis of aspirin tablets on a microscale

Try this microscale class practical to analyse aspirin tablets and find out how much salicylic acid is present. Includes kit list and safety instructions.

The temperature changes induced by evaporation

Explore the rate of evaporation for a trio of liquids, using just a temperature strip, and our worksheet. Includes kit list and safety instructions.

Properties of stereoisomers

By soaking cotton wool in two limonene enantiomers, and adding a stereoisomer, students can explore the differences between each chemical and discuss how they each might react in different conditions. Includes kit list and safety instructions.

Using a microscale conductivity meter

Explore electrical conductivity with this practical that allows students to test different materials for how well a current will pass through them. Includes kit list and safety instructions.

Microscale extraction of copper

In association with Nuffield Foundation

Try this practical to reduce copper(II) oxide to copper using hydrogen, revealing their positions in the reactivity series. Includes kit list and safety instructions.

Practical potions microscale | 11–14 years

Observe chemical changes in this microscale experiment with a spooky twist.