All Medicinal chemistry articles – Page 6
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FeatureRe-arming the antibiotic arsenal
With drug-resistant bacteria constantly in the news, what is being done to develop better treatments? Phillip Broadwith takes a look
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ResourceFaces of Chemistry – Reckitt Benckiser: Gaviscon
Go behind the scenes of the Research and Development department that created Gaviscon.
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FeatureOne in the eye for river blindness
It’s one of the greatest success stories in human health – a drug created from a product found in nature and given away freely to those who most need it, saving millions from debilitating blindness. Ian Farrell investigates the marvel of ivermectin
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ReviewMedicinal chemistry: the modern drug discovery process
An introduction to the development of new drugs, well suited to undergraduates studying medicinal chemistry and the pharmaceutical sciences, particularly those at the beginning of their studies
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ResourceChemistry Now: Combinatorial Chemistry
Combinatorial chemistry is a group of techniques for synthesising large arrays of related chemicals and is increasingly being used by pharmaceutical companies in their search for new drugs.
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Lesson planChemistry masterclass
Undertake the work of a medicinal chemist by isolating an active compound. Find the kit list, safety instructions and session timings in the download
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ResourceLaboratory and Pilot Plant Tours
Take a virtual tour of the areas where chemists work. The chemistry laboratories do initial research and the pilot plant is involved in making pharmaceutical products on a large scale. Key equipment and activities are highlighted. Courtesy of the ABPI.
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ResourceOn This Day – Aug 10 : Synthesis of aspirin
Aspirin was one of the first drugs to become commercial available and is still the most widely used drug in the world. Approximately 35,000 metric tonnes are produced and consumed each year – that’s enough to make more than 100 billion aspirin tablets.
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ResourceOn This Day - Mar 11 : Alexander Fleming died
He discovered the antibiotic penicillin, which was the first of many antibiotic drugs that successfully treated a variety of bacterial diseases. This discovery earned him part of the Nobel Prize in Physiology or Medicine in 1945, shared with Ernst Chain and Howard Florey.
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ResourceOn This Day - Oct 01 : Thalidomide was marketed
This notorious drug was marketed as a mild sleeping pill that was safe even for pregnant women. It wasn’t until 1962 that the severe side effects were revealed, where it had caused the development of malformed limbs in babies.
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ResourceOn This Day - Oct 03 : Charles Pedersen was born
He shared the 1987 Nobel Prize in Chemistry for the synthesis of crown ethers. These are a group of compounds that can “recognize” each other and choose which other molecules to form complexes, much like the behaviour of molecules found in living organisms.