All Medicinal chemistry articles – Page 2
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FeatureAntibiotics: solving an evolving problem
Includes curriculum-linked resources to use in your classroom
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Resource
The microscale synthesis of aspirin
Carry out a microscale esterification reaction between 2-hydroxybenzoic acid (salicylic acid) and ethanoic anhydride using phosphoric acid as a catalyst to produce aspirin on a microscale
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Resource
Aspirin screen experiment
Get students aged 16–18 running their own organic synthesis on a computer or tablet before taking part in the real thing. This resource also features an in-depth practical guide and a set of worksheets covering the theory.
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Opinion
Students don’t appreciate what chemistry can do
Is this causing the dip in applications to university chemistry courses?
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Magnificent molecules
Acetylcysteine
Peleton Source: Christopher Strickland / Shutterstock.com The peleton of the Tour of Britain near Mellerstain, Kelso in the Scottish Borders, September 2017 Peleton Source: Christopher Strickland / Shutterstock.com The peleton of the Tour of Britain near Mellerstain, Kelso ...
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News
Targeting manganese fights the flu
A tweak allows a promising flu-fighting compound to latch onto both of the manganese atoms at the heart of a flu enzyme
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Resource
Organic chemists: Fighting blindness
The RSC Organic Division Council have developed scientific case-studies to highlight the importance of organic synthesis in every aspect of life.
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Resource
New drugs for old: pharmaceuticals
This is a problem-based case study looks at the isolation, identification and synthesis of a pharmaceutical drug. Students are involved in screening natural herbal remedies for their active ingredients.
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Experiment
Using indigestion tablets to neutralise an acid
Investigate and measure the neutralising effect of indigestion tablets on hydrochloric acid in this class practical. Includes kit list and safety instructions.
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Resource
Advanced Medicinal Chemistry
This course material gives real-life examples of drug discovery and information on the drug discovery process through an industrial context, produced by Dr Ray Leslie of NTU and AstraZeneca.
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Resource
Aspirin book
This book contains eight free-standing activities that can be used singly or as a coherent package in a wide range of teaching and learning situations for both academic and vocational courses.
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Resource
Chemistry in your cupboard: Nurofen
Link the post-16 topics of bonding and solubility, isomerisation and reactions of organic functional groups to the topic of analgesics. Learn about a range of real life contexts for these chemical ideas through written material, and questions to encourage learning and test understanding.
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Resource
Challenging Medicines: Physiochemical Properties - Practicals
Practical experiments associated with the handouts for Physiochemical Properties. Investigating the dissolution, pKₐ and rates of hydrolysis of everyday tablets are covered.
