All Medicinal chemistry articles – Page 3
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ExperimentUsing indigestion tablets to neutralise an acid
Investigate and measure the neutralising effect of indigestion tablets on hydrochloric acid in this class practical. Includes kit list and safety instructions.
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Resource
Advanced Medicinal Chemistry
This course material gives real-life examples of drug discovery and information on the drug discovery process through an industrial context, produced by Dr Ray Leslie of NTU and AstraZeneca.
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Aspirin book
This book contains eight free-standing activities that can be used singly or as a coherent package in a wide range of teaching and learning situations for both academic and vocational courses.
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Chemistry in your cupboard: Nurofen
Link the post-16 topics of bonding and solubility, isomerisation and reactions of organic functional groups to the topic of analgesics. Learn about a range of real life contexts for these chemical ideas through written material, and questions to encourage learning and test understanding.
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Challenging Medicines: Physiochemical Properties - Practicals
Practical experiments associated with the handouts for Physiochemical Properties. Investigating the dissolution, pKₐ and rates of hydrolysis of everyday tablets are covered.
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Molecules against malaria
This medicinal chemistry case study is designed to introduce students to the development of antimalarial 4-aminoquinolines and the early stages of drug discovery and development. It focuses on antimalarial 4-aminoquinolines (4-AQs) and involves an introduction to malaria, its causes, societal impact and the need for new drugs. It then presents ...
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Challenging Medicines: Introduction/Pedagogical Overview
Medicines and the development of pharmaceutical drugs have the potential to help us take on the challenge of human health - Improving and maintaining accessible health, including disease prevention.
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Challenging Medicines: Physiochemical Properties
These resource sheets look at the different physiochemical properties of medicines. Pharmacokinetic processes, dissolution, ionisation and dissociation are all covered here.
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Challenging Medicines: Making Medicines - Practicals and PPT
These resources show the extent to which everyday medicines can be made in the classroom. Using straightforward processes milk of magnesia and ear drops can all be made.
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Magnificent molecules
Caesium chloride
A versatile compound used in cancer treatment, solar cells and even making beer
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News
Route to fiendishly complex marine molecule cut in half
Shortcut to promising natural product already in Alzheimer’s and HIV trials
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Review
An introduction to medicinal chemistry
This textbook for undergraduates is now in its 6th edition
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News
Responsive nanoparticles target sight-stealing fungus
Eye drop tricks fungal eye infection into self-destruction
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Resource
On This Day - Feb 27 : Aspirin was patented
Aspirin, also known as acetylsalicylic acid, was initially used as a painkiller. Aspirin is also used as a preventative medicine against strokes, blood clots and heart attacks due to its antiplatelet effect
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Magnificent molecules
Diazepam
One of the biggest selling pharmaceuticals in history, the ‘mother’s little helper’
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