All Medicinal chemistry articles – Page 3
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OpinionStudents don’t appreciate what chemistry can do
Is this causing the dip in applications to university chemistry courses?
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Magnificent molecules
Acetylcysteine
Peleton Source: Christopher Strickland / Shutterstock.com The peleton of the Tour of Britain near Mellerstain, Kelso in the Scottish Borders, September 2017 Peleton Source: Christopher Strickland / Shutterstock.com The peleton of the Tour of Britain near Mellerstain, Kelso in the Scottish Borders, September ...
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News
Targeting manganese fights the flu
A tweak allows a promising flu-fighting compound to latch onto both of the manganese atoms at the heart of a flu enzyme
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Resource
Organic chemists: Fighting blindness
The RSC Organic Division Council have developed scientific case-studies to highlight the importance of organic synthesis in every aspect of life.
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Resource
New drugs for old: pharmaceuticals
This is a problem-based case study looks at the isolation, identification and synthesis of a pharmaceutical drug. Students are involved in screening natural herbal remedies for their active ingredients.
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Experiment
Using indigestion tablets to neutralise an acid
Investigate and measure the neutralising effect of indigestion tablets on hydrochloric acid in this class practical. Includes kit list and safety instructions.
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Resource
Advanced Medicinal Chemistry
This course material gives real-life examples of drug discovery and information on the drug discovery process through an industrial context, produced by Dr Ray Leslie of NTU and AstraZeneca.
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Resource
Aspirin book
This book contains eight free-standing activities that can be used singly or as a coherent package in a wide range of teaching and learning situations for both academic and vocational courses.
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Resource
Chemistry in your cupboard: Nurofen
Link the post-16 topics of bonding and solubility, isomerisation and reactions of organic functional groups to the topic of analgesics. Learn about a range of real life contexts for these chemical ideas through written material, and questions to encourage learning and test understanding.
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Resource
Challenging Medicines: Physiochemical Properties - Practicals
Practical experiments associated with the handouts for Physiochemical Properties. Investigating the dissolution, pKₐ and rates of hydrolysis of everyday tablets are covered.
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Resource
Molecules against malaria
This medicinal chemistry case study is designed to introduce students to the development of antimalarial 4-aminoquinolines and the early stages of drug discovery and development. It focuses on antimalarial 4-aminoquinolines (4-AQs) and involves an introduction to malaria, its causes, societal impact and the need for new drugs. It then presents ...
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Resource
Challenging Medicines: Introduction/Pedagogical Overview
Medicines and the development of pharmaceutical drugs have the potential to help us take on the challenge of human health - Improving and maintaining accessible health, including disease prevention.
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Resource
Challenging Medicines: Physiochemical Properties
These resource sheets look at the different physiochemical properties of medicines. Pharmacokinetic processes, dissolution, ionisation and dissociation are all covered here.
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Resource
Challenging Medicines: Making Medicines - Practicals and PPT
These resources show the extent to which everyday medicines can be made in the classroom. Using straightforward processes milk of magnesia and ear drops can all be made.
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Magnificent molecules
Caesium chloride
A versatile compound used in cancer treatment, solar cells and even making beer
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News
Route to fiendishly complex marine molecule cut in half
Shortcut to promising natural product already in Alzheimer’s and HIV trials
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Review
An introduction to medicinal chemistry
This textbook for undergraduates is now in its 6th edition
