All Medicinal chemistry articles – Page 3
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ResourceChemistry in your cupboard: Nurofen
Link the post-16 topics of bonding and solubility, isomerisation and reactions of organic functional groups to the topic of analgesics. Learn about a range of real life contexts for these chemical ideas through written material, and questions to encourage learning and test understanding.
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Challenging Medicines: Physiochemical Properties - Practicals
Practical experiments associated with the handouts for Physiochemical Properties. Investigating the dissolution, pKₐ and rates of hydrolysis of everyday tablets are covered.
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Molecules against malaria
This medicinal chemistry case study is designed to introduce students to the development of antimalarial 4-aminoquinolines and the early stages of drug discovery and development. It focuses on antimalarial 4-aminoquinolines (4-AQs) and involves an introduction to malaria, its causes, societal impact and the need for new drugs. It then presents ...
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Challenging Medicines: Introduction/Pedagogical Overview
Medicines and the development of pharmaceutical drugs have the potential to help us take on the challenge of human health - Improving and maintaining accessible health, including disease prevention.
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Challenging Medicines: Physiochemical Properties
These resource sheets look at the different physiochemical properties of medicines. Pharmacokinetic processes, dissolution, ionisation and dissociation are all covered here.
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Challenging Medicines: Making Medicines - Practicals and PPT
These resources show the extent to which everyday medicines can be made in the classroom. Using straightforward processes milk of magnesia and ear drops can all be made.
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Magnificent molecules
Caesium chloride
A versatile compound used in cancer treatment, solar cells and even making beer
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News
Route to fiendishly complex marine molecule cut in half
Shortcut to promising natural product already in Alzheimer’s and HIV trials
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Review
An introduction to medicinal chemistry
This textbook for undergraduates is now in its 6th edition
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News
Responsive nanoparticles target sight-stealing fungus
Eye drop tricks fungal eye infection into self-destruction
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On This Day - Feb 27 : Aspirin was patented
Aspirin, also known as acetylsalicylic acid, was initially used as a painkiller. Aspirin is also used as a preventative medicine against strokes, blood clots and heart attacks due to its antiplatelet effect
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Magnificent molecules
Diazepam
One of the biggest selling pharmaceuticals in history, the ‘mother’s little helper’
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Magnificent molecules
Spilanthol
Jen Newton finds the active molecule in electric daisies is not to her taste
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News
Gold nanoclusters offer route to better vaccines
New technique improves immune response and safety of hepatitis E vaccine
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Recycling the undesired enantiomer of Naproxen
This context/problem-based learning (C/PBL) resource is part of a collection we have commissioned for you to use with your undergraduate students. This 5 credit module is based on the following scenario: Your students work for a company that produces (S)-naproxen, a non-steroidal anti-inflammatory drug (NSAID), via a racemic method. ...
