All Drug discovery and development articles – Page 2
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Resource
New drugs for old: pharmaceuticals
This is a problem-based case study looks at the isolation, identification and synthesis of a pharmaceutical drug. Students are involved in screening natural herbal remedies for their active ingredients.
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News
Route to fiendishly complex marine molecule cut in half
Shortcut to promising natural product already in Alzheimer’s and HIV trials
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Feature
Exceptional enzymes
New biological catalysts could deliver useful chemicals chemistry cannot make
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Soundbite
A real fake tan: melanin minus mutation
Rowan Frame explains how a new drug might make sunburn a thing of the past
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News
Responsive nanoparticles target sight-stealing fungus
Eye drop tricks fungal eye infection into self-destruction
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News
15-minute test catches out flu virus
A cheap, portable setup to detect influenza viruses could help clinicians prescribe the right drugs
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Magnificent molecules
Diazepam
One of the biggest selling pharmaceuticals in history, the ‘mother’s little helper’
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News
Gold nanoclusters offer route to better vaccines
New technique improves immune response and safety of hepatitis E vaccine
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News
Smart bandages you press for antibacterial action
Only releasing antibacterials when needed leave bacteria with no time to adapt
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Feature
Africa’s gift to the world
Raymond Cooper and Jeffrey Deakin explain how a tiny plant from Madagascar, known as the rosy periwinkle, is helping in the fight against cancer
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Feature
The challenge of turning industrial chemistry green
Green chemistry is a maturing discipline. But the subject still holds big challenges that the next generation of chemists must tackle, as Josh Howgego reports
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Feature
Re-arming the antibiotic arsenal
With drug-resistant bacteria constantly in the news, what is being done to develop better treatments? Phillip Broadwith takes a look
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News
Caffeine-fuelled fix for runaway eye treatment
Crystal designed to have stronger hydrogen bonds
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Feature
One in the eye for river blindness
It’s one of the greatest success stories in human health – a drug created from a product found in nature and given away freely to those who most need it, saving millions from debilitating blindness. Ian Farrell investigates the marvel of ivermectin
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Review
Medicinal chemistry: the modern drug discovery process
An introduction to the development of new drugs, well suited to undergraduates studying medicinal chemistry and the pharmaceutical sciences, particularly those at the beginning of their studies
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