All Drug discovery and development articles – Page 3

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    From molecules to medicines


    Turning an active drug molecule into a finished product requires as much chemistry as developing the drug in the first place, as Phillip Broadwith discovers.

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    Ruthenium compounds as anticancer agents


    New ruthenium-based compounds with fewer and less severe side effects, could replace longstanding platinum-based anticancer drugs

  • Jessica Kershaw
    The Mole

    A day in the life of a trainee patent attorney: Jessica Kershaw


    Jessica Kershaw has spent the past four months as a trainee patent attorney for Carpmaels & Ransford, London. She talks to Tom Westgate about her typical day

  • Tomorrow's vaccines - designed and made in the lab

    Synthetic vaccines


    The design of synthetic vaccines offers a more systematic approach to vaccine therapy for many illnesses, including cancer, and even drug addiction

  • A woman sneezing
    The Mole

    Pandemic swine flu


    Should we be worried by the pandemic this autumn and winter?

  • Kew's greenhouse
    The Mole

    Kew the celebrations


    The Royal Botanic Gardens, Kew, celebrates 250 years of horticulture and science.

  • Electrical discharges from the nerve cells in the brain

    Epilepsy - beyond bromide


    An historical journey into the treatment of epilepsy, starting with potassium bromide 150 years ago

  • Feet on weighing scales
    The Mole

    Obesity – at what cost


    Do drugs have a part to play in controlling obesity?

  • mosquito
    The Mole

    Antimalarial drugs


    Approximately one million people die annually from malaria worldwide. Tragically, 90 per cent of these deaths are among the under-fives in sub-Saharan Africa, who have little if any access to adequate healthcare. Drugs are used to treat the disease but parasitic resistance to these drugs is growing, so what is the alternative?

  • David Carling
    The Mole

    A day in the life of a trainee patent attorney: David Carling


    David has spent the past six months working as a trainee patent attorney for Potter Clarkson LLP. He talks to Rachel Bolton-King about his typical day

  • image - brown mosquito

    Artemisinin and a new generation of antimalarial drugs


    Every year between one and two million people - mainly children - living in the tropics and subtropics die of malaria.

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    Pain relief: from coal tar to paracetamol


    Analgesics, ie pain-relieving drugs, fall into two categories: those that also reduce body temperature in fevers (antipyretics), and those that act mainly on the brain - typically morphine and diamorphine/heroin. Here we consider members of the first group, particularly those once designated 'coal tar analgesics'. Paracetamol, our most popular over-the-counter pain killer, is one of these.