All Drug discovery and development articles – Page 3
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FeatureRe-arming the antibiotic arsenal
With drug-resistant bacteria constantly in the news, what is being done to develop better treatments? Phillip Broadwith takes a look
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NewsCaffeine-fuelled fix for runaway eye treatment
Crystal designed to have stronger hydrogen bonds
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FeatureOne in the eye for river blindness
It’s one of the greatest success stories in human health – a drug created from a product found in nature and given away freely to those who most need it, saving millions from debilitating blindness. Ian Farrell investigates the marvel of ivermectin
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ReviewMedicinal chemistry: the modern drug discovery process
An introduction to the development of new drugs, well suited to undergraduates studying medicinal chemistry and the pharmaceutical sciences, particularly those at the beginning of their studies
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FeatureRuthenium compounds as anticancer agents
New ruthenium-based compounds with fewer and less severe side effects, could replace longstanding platinum-based anticancer drugs
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The MoleA day in the life of a trainee patent attorney: Jessica Kershaw
Jessica Kershaw has spent the past four months as a trainee patent attorney for Carpmaels & Ransford, London. She talks to Tom Westgate about her typical day
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FeatureSynthetic vaccines
The design of synthetic vaccines offers a more systematic approach to vaccine therapy for many illnesses, including cancer, and even drug addiction
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The MoleKew the celebrations
The Royal Botanic Gardens, Kew, celebrates 250 years of horticulture and science.
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FeatureEpilepsy - beyond bromide
An historical journey into the treatment of epilepsy, starting with potassium bromide 150 years ago
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The MoleAntimalarial drugs
Approximately one million people die annually from malaria worldwide. Tragically, 90 per cent of these deaths are among the under-fives in sub-Saharan Africa, who have little if any access to adequate healthcare. Drugs are used to treat the disease but parasitic resistance to these drugs is growing, so what is the alternative?
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The MoleA day in the life of a trainee patent attorney: David Carling
David has spent the past six months working as a trainee patent attorney for Potter Clarkson LLP. He talks to Rachel Bolton-King about his typical day
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FeatureArtemisinin and a new generation of antimalarial drugs
Every year between one and two million people - mainly children - living in the tropics and subtropics die of malaria.
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FeaturePain relief: from coal tar to paracetamol
Analgesics, ie pain-relieving drugs, fall into two categories: those that also reduce body temperature in fevers (antipyretics), and those that act mainly on the brain - typically morphine and diamorphine/heroin. Here we consider members of the first group, particularly those once designated 'coal tar analgesics'. Paracetamol, our most popular over-the-counter pain killer, is one of these.
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